Page 2 - ABUS-Casestudy

Improve cancer detection with ABUS

Results from multiple large scale screening ultrasound studies Studies show that
involving thousands of women demonstrate that ultrasound improves mammography misses
cancer detection as a supplement to mammography. The EASY Study
(European Asymptomatic Screening Study) shows that it is feasible one-third
to implement 3D ABUS into a high-volume mammography center of cancers in patients
and increase the cancer detection rate while maintaining a low recall with dense breasts.
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rate well within the recommendations of the European guidelines for
quality assurance in breast cancer screening and diagnosis. 4

Designed especially for screening, the sensitivity of the GE HealthCare
Invenia ABUS 2.0 is not affected by dense tissue, allowing the detection 2.4 additional
™
of non-calcified carcinomas that are obscured in mammography. Major cancers detected per
advantages include providing a volumetric global visualization of
the whole breast, and the exams are standardized and reproducible, 1000 women screened. 4
enabling batch reading and double reading of 3D ABUS and allowing
a comparison with previous volumes. 5

EUSOBI guidelines: supplemental screening Women whose breast
for breast density cancer is detected at an
EUSOBI recent guidelines recommend tailored screening programs that early stage have a
take the ‘characteristics and personal wishes of individual women into
account.’ EUSOBI now additionally recommends that women should 90% or higher
be informed about their breast density and the implications of having survival rate. 8
dense breasts. EUSOBI recommends that supplemental screening is
recommended in women with extremely dense breasts – in particular,
EUSOBI recommends where MRI screening is unavailable, ultrasound in
combination with mammography may be used as an alternative. 6
The recent introduction of the U.S. Food & Drug Administration
(FDA) mandate to inform all women of their breast density in their
mammography letters reinforces the global movement to enhance
screening women with dense breasts and move away from a
one-size-fits-all approach.

Why perform different exams?
Imaging techniques differ in the characteristics of cancers detected.
This can be seen in everyday practice with mammography, ultrasound
and MRI of the breast. Each imaging tool should be specifically used for
its proven benefits and a combined approach can further characterize
findings and improve sensitivity.

There is a significant breast cancer detection benefit when using
screening ultrasound to supplement annual mammography in
women with dense breasts. ABUS coupled with tomosynthesis provides
optimization of sensitivity while reducing false positives. This
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combined approach is the most advantageous screening choice
for most women with dense breasts.

Supplemental screening with Invenia ABUS 2.0 transforms breast care
from reactive to proactive. Women whose breast cancer is detected at
an early stage have a 90% or higher survival rate. 8